51 products were found matching "K00058"!
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D-3-phosphoglycerate dehydrogenase (PHGDH), partial,...
Item number: CSB-EP017920HU1.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 2-251aa. Protein Length: Partial. Tag Info: N-terminal GST-tagged. Target Protein Sequence: AFANLRKVLI SDSLDPCCRK ILQDGGLQVV EKQNLSKEEL IAELQDCEGL IVRSATKVTA DVINAAEKLQ VVGRAGTGVD NVDLEAATRK GILVMNTPNG NSLSAAELTC GMIMCLARQI PQATASMKDG KWERKKFMGT...
| Keywords: | PGDH3, PHGDH, 3-PGDH, Malate dehydrogenase, 2-oxoglutarate reductase, D-3-phosphoglycerate dehydrogenase |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 54.3 kD |
From 247.00€
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D-3-phosphoglycerate dehydrogenase (PHGDH), partial,...
Item number: CSB-EP017920HU1c0.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 2-251aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-GST-tagged. Target Protein Sequence: AFANLRKVLI SDSLDPCCRK ILQDGGLQVV EKQNLSKEEL IAELQDCEGL IVRSATKVTA DVINAAEKLQ VVGRAGTGVD NVDLEAATRK GILVMNTPNG NSLSAAELTC GMIMCLARQI PQATASMKDG...
| Keywords: | PGDH3, PHGDH, 3-PGDH, Malate dehydrogenase, 2-oxoglutarate reductase, D-3-phosphoglycerate dehydrogenase |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 58.3 kD |
From 247.00€
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NCT-503
Item number: TGM-T4213-100mg
Description: NCT-503 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH), inhibiting serine synthesis from 3-phosphoglycerate in cells. Target: FLT, Dehydrogenase, TAM Receptor. Smiles: Cc1cc(C)nc(NC(=S)N2CCN(Cc3ccc(cc3)C(F)(F)F)CC2)c1. References: Pacold ME, et al. A PHGDH inhibitor reveals coordination...
| Keywords: | NCT 503 |
| Application: | PHGDH inhibitor |
| CAS | 1916571-90-8 |
| MW: | 408.48 D |
From 37.00€
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PHGDH Protein, Human, Recombinant (His)
Item number: TGM-TMPY-02801-100ug
Description: PHGDH is a member of the D-isomer specific 2-hydroxyacid dehydrogenase family. This new family consists of D-isomer-stereospecific enzymes. The conserved residues in this family appear to be the residues involved in the substrate binding and the catalytic reaction, and thus to be targets for...
| Keywords: | 3-PGDH, PGD, PDG, PGDH, NLS, SERA, PGAD, 3PGDH, NLS1, phosphoglycerate dehydrogenase, HEL-S-113, PHGDHD |
| MW: | 58 kD |
From 427.00€
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NCT-502
Item number: TGM-T16277-100mg
Description: NCT-502 (N-(4,6-dimethylpyridin-2-yl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbothioamide) is a human phosphoglycerate dehydrogenase inhibitor, cytotoxic to PHGDH-dependent cancer cells. It decreases glucose-derived serine production and it has an IC50 of 3.7 µM against PHGDH. Target:...
| Keywords: | N-(4,6-dimethylpyridin-2-yl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbothioamide |
| Application: | PHGDH inhibitor |
| CAS | 1542213-00-2 |
| MW: | 395.45 D |
From 34.00€
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CBR-5884
Item number: TGM-T14884-100mg
Description: CBR-5884 is an selective, active of phosphoglycerate dehydrogenase (PHGDH) inhibitor with an IC50 of 33 µM. CBR-5884 inhibits de novo serine synthesis in cancer cells and is selectively toxic to cancer cell lines with high serine biosynthetic activity. CBR-5884 selectively inhibits the proliferation of...
| Application: | PHGDH inhibitor |
| CAS | 681159-27-3 |
| MW: | 336.39 D |
From 40.00€
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D-(-)-3-Phosphoglyceric acid disodium
Item number: TGM-T37185-10mg
Description: D-(-)-3-Phosphoglyceric acid disodium (3-Phospho-D-glyceric acid disodium) is an intermediate in glycolysis/gluconeogenesis and the biosynthesis of serine, glycine, and threonine, competitively inhibiting yeast enolase. It also functions as an intermediate in biosynthetic pathways in plants, eukaryotes,...
| Keywords: | 3-Phospho-D-glyceric acid disodium |
| Application: | Glycolysis intermediate, serine precursor |
| CAS | 80731-10-8 |
| MW: | 230.02 D |
From 198.00€
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Anti-PHGDH
Item number: CSB-PA03255A0Rb.100
Host Species: Rabbit. Isotype: IgG. Buffer: Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: >95%, Protein G purified. Target Name: PHGDH. Antigen Species: Human
| Keywords: | Anti-PHGDH, Anti-PGDH3, Anti-3-PGDH, Anti-Malate dehydrogenase, Anti-2-oxoglutarate reductase, Anti-D-3-phosphoglycerate... |
| Application: | ELISA, WB, IHC, IF |
| Host: | Rabbit |
| Species reactivity: | human |
From 167.00€
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Anti-PHGDH
Item number: CSB-PA03257A0Rb.100
Host Species: Rabbit. Isotype: IgG. Buffer: Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: >95%, Protein G purified. Target Name: PHGDH. Antigen Species: Human
| Keywords: | Anti-PHGDH, Anti-PGDH3, Anti-3-PGDH, Anti-Malate dehydrogenase, Anti-2-oxoglutarate reductase, Anti-D-3-phosphoglycerate... |
| Application: | ELISA, WB, IHC |
| Host: | Rabbit |
| Species reactivity: | human |
From 167.00€
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Anti-PHGDH
Item number: CSB-PA056095.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: PHGDH. Antigen Species: Human
| Keywords: | Anti-PHGDH, Anti-PGDH3, Anti-3-PGDH, Anti-Malate dehydrogenase, Anti-2-oxoglutarate reductase, Anti-D-3-phosphoglycerate... |
| Application: | ELISA, WB |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 167.00€
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Anti-PHGDH
Item number: CSB-PA794903.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: PHGDH. Antigen Species: Human
| Keywords: | Anti-PHGDH, Anti-PGDH3, Anti-3-PGDH, Anti-Malate dehydrogenase, Anti-2-oxoglutarate reductase, Anti-D-3-phosphoglycerate... |
| Application: | ELISA, WB |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 167.00€
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CBR-5884
Item number: Cay19236-5
CBR-5884 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH), inhibiting serine synthesis from 3-phosphoglycerate in cells with an IC50 value of 33 µM. It does not affect other NAD+-dependent dehydrogenases, including lactate dehydrogenase and malate dehydrogenase 1. CBR-5884 inhibits the proliferation of...
| Keywords: | 5-[(2-furanylcarbonyl)amino]-3-methyl-4-thiocyanato-2-thiophenecarboxylic acid, ethyl ester |
| Application: | PHGDH inhibitor |
| CAS | 681159-27-3 |
| MW: | 336.4 D |
From 35.00€
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