56 products were found matching "K00033"!

0.5mg/ml if reconstituted with 0.2ml sterile DI water. 6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of...

An intermediate in the pentose phosphate pathway, inhibits glucose-6-phosphate isomerase (Kis = 48 and 42 µM using glucose-6-phosphate or fructose-6-phosphate as the substrates, respectively), has been used as a cross-linking agent in the formation of hydrogels, has been conjugated to nanoparticles to modulate zeta...

6-phosphogluconate dehydrogenase (6-PGDH) is the rate-limiting enzyme of the pentose phosphate pathway, which is responsible for the production of NADPH, energy balance, growth rate, and cell viability. 6-PGDH is also associated with a variety of tumor signaling pathways, including epidermal growth factor signaling...

6-Aminonicotinamide (6-AN) is a well-established inhibitor of the NADP+-dependent enzyme, 6-phosphogluconate dehydrogenase (Ki = 0.46 µM). Through this action, 6-AN interferes with glycolysis, resulting in ATP depletion and synergizes with DNA-crosslinking chemotherapy drugs, like cisplatin, in killing cancer cells...

Physcion is a natural anthraquinone. It has been reported to have laxative and anti-inflammatory actions, inhibit kinases and tyrosinase, and have cytotoxicity against cancer cells. Physcion inhibits 6-phosphogluconate dehydrogenase (IC50 = 38.5 µM), decreasing lipogenesis and RNA biosynthesis in cancer cells,...

Description: Physcion (Physcione) (Parietin) is an anthraquinone isolated from traditional Chinese medicine Radix et Rhizoma Rhei, acts as an inhibitor of 6-phosphogluconate dehydrogenase, with an IC50 and a Kd of 38.5 µM and 26.0 µM, respectively. Physcion (Parietin) exhibits laxative, hepatoprotective,...

Protein function: Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. [The UniProt Consortium]

Protein function: Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. [The UniProt Consortium]

Protein function: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 94%...

Protein function: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 98%...

In 1X PBS, pH 7.4, with 0.09% sodium azide. 6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate...

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 4-483aa. Protein Length: Partial. Tag Info: N-terminal GST-tagged. Target Protein Sequence: ADIALIGLAV MGQNLILNMN DHGFVVCAFN RTVSKVDDFL ANEAKGTKVV GAQSLKEMVS KLKKPRRIIL LVKAGQAVDD FIEKLVPLLD TGDIIIDGGN SEYRDTTRRC RDLKAKGILF VGSGVSGGEE GARYGPSLMP...