175 products were found matching "K00016"!

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GNE-140
GNE-140

Item number: Cay39015-10

GNE-140 is an inhibitor of lactate dehydrogenase A (LDHA) and LDHB (IC50s = 3 and 5 nM, respectively). It reduces lactate production in MiaPaCa-2 pancreatic cancer cells (IC50 = 670 nM). GNE-140 decreases proliferation in a panel of 37 cancer cell lines when used at a concentration of 5 µM. Formal name:...
Keywords: 3-[(2-chlorophenyl)thio]-5,6R-dihydro-4-hydroxy-6-[4-(4-morpholinyl)phenyl]-6-(3-thienyl)-2(1H)-pyridinone
Application: LDHA/LDHB inhibitor
CAS 2003234-63-5
MW: 499 D
From 127.00€ *
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LDH Cytotoxicity Assay Kit
LDH Cytotoxicity Assay Kit

Item number: Cay601170-96

Necrosis is accompanied by mitochondrial swelling and increased plasma membrane permeability, while apoptosis involves an articulated breakdown of the cell into membrane-bound apoptotic bodies. Lactate dehydrogenase (LDH) is a soluble cytosolic enzyme that is released into the culture medium following loss of...
Keywords: Lactate Dehydrogenase Cytotoxicity Assay Kit
Application: Cell based assays
Species reactivity: broad
From 105.00€ *
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Rat LDHA (Lactate Dehydrogenase A) ELISA Kit
Rat LDHA (Lactate Dehydrogenase A) ELISA Kit

Item number: ELK-ELK7572.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat LDHA. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat LDHA. Next,...
Keywords: Ldha, LDH-A, Ldh-1, LDH-M, LDH muscle subunit, L-lactate dehydrogenase A chain
Application: ELISA
Species reactivity: rat
365.00€ * From 328.50€ *
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Rat LDHB (Lactate Dehydrogenase B) ELISA Kit
Rat LDHB (Lactate Dehydrogenase B) ELISA Kit

Item number: ELK-ELK7736.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat LDHB. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat LDHB. Next,...
Keywords: Ldhb, LDH-B, Ldh-2, LDH-H, LDH heart subunit, L-lactate dehydrogenase B chain
Application: ELISA
Species reactivity: rat
365.00€ * From 328.50€ *
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Human LDHA (Lactate Dehydrogenase A) ELISA Kit
Human LDHA (Lactate Dehydrogenase A) ELISA Kit

Item number: ELK-ELK1900.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human LDHA. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human LDHA. Next,...
Keywords: LDH-A, LDH-M, PIG19, LDH muscle subunit, L-lactate dehydrogenase A chain, Renal carcinoma antigen NY-REN-59, Cell...
Application: ELISA
Species reactivity: human
365.00€ * From 328.50€ *
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Human LDHB (Lactate Dehydrogenase B) ELISA Kit
Human LDHB (Lactate Dehydrogenase B) ELISA Kit

Item number: ELK-ELK2155.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human LDHB. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human LDHB. Next,...
Keywords: LDHB, LDH-B, LDH-H, LDH heart subunit, L-lactate dehydrogenase B chain, Renal carcinoma antigen NY-REN-46
Application: ELISA
Species reactivity: human
365.00€ * From 328.50€ *
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Human LDHC (Lactate Dehydrogenase C) ELISA Kit
Human LDHC (Lactate Dehydrogenase C) ELISA Kit

Item number: ELK-ELK3881.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human LDHC. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human LDHC. Next,...
Keywords: CT32, LDH3, LDHC, LDH-C, LDH-X, EC=1.1.1.27, LDH testis subunit, Cancer/testis antigen 32, L-lactate dehydrogenase C chain
Application: ELISA
Species reactivity: human
365.00€ * From 328.50€ *
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Mouse LDHB (Lactate Dehydrogenase B) ELISA Kit
Mouse LDHB (Lactate Dehydrogenase B) ELISA Kit

Item number: ELK-ELK5673.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse LDHB. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse LDHB. Next,...
Keywords: Ldhb, LDH-B, Ldh-2, LDH-H, LDH heart subunit, L-lactate dehydrogenase B chain
Application: ELISA
Species reactivity: mouse
365.00€ * From 328.50€ *
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FX11
FX11

Item number: Cay38518-1

FX11 is an inhibitor of lactate dehydrogenase-A (LDH-A, Ki = 8 µM). It is selective for LDH-A over GAPDH (Ki = >300 µM). FX11 increases oxygen consumption and the production of reactive oxygen species (ROS), as well as induces cell death in P493-6 lymphoblastoid cells. In vivo, FX11 (42 µg/animal, i.p.) reduces...
Keywords: 2,3-dihydroxy-6-methyl-7-(phenylmethyl)-4-propyl-1-naphthalenecarboxylic acid
Application: LDH-A (lactate dehydrogenase-A) inhibitor
CAS 213971-34-7
MW: 350.4 D
From 44.00€ *
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Sodium Oxamate
Sodium Oxamate

Item number: Cay19057-5

Sodium oxamate is a derivative of pyruvate that inhibits the conversion of pyruvate to lactate via lactate dehydrogenase, thus disrupting glycolysis. Because cancer cells produce a large amount of energy via aerobic glycolysis, sodium oxamate has been studied as an inhibitor of carbohydrate metabolism in various...
Keywords: Oxalic Acid monoamide, Oxamic Acid, 2-amino-2-oxo-acetic acid, monosodium salt
Application: Glycolysis disruptor, Lactate dehydrogenase inhibitor
CAS 565-73-1
MW: 111 D
From 80.00€ *
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GSK2837808A
GSK2837808A

Item number: Cay20626-1

GSK2837808A is a potent inhibitor of lactate dehydrogenase (LDH) A and B (IC50s = 2.6 and 0.43 nM, for human recombinant LDHA and LDHB, respectively). It inhibits lactate production in Snu398 hepatocellular carcinoma cells in which LDHB expression is undetectable (EC50 = 400 nM). GSK2837808A (10 µM) reduces glucose...
Keywords: 3-[[3-[(cyclopropylamino)sulfonyl]-7-(2,4-dimethoxy-5-pyrimidinyl)-4-quinolinyl]amino]-5-(3,5-difluorophenoxy)-benzoic acid
Application: LDHA inhibitor
CAS 1445879-21-9
MW: 649.6 D
From 60.00€ *
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Galloflavin
Galloflavin

Item number: Cay14846-5

Galloflavin is an inhibitor of both the A and B isoforms of lactate dehydrogenase (Kis = 5.46 and 15.06 µM, respectively). It has been shown to prevent proliferation of many different cancer cell lines in vitro by blocking glycolysis and ATP production.Formal Name:...
Keywords: NSC 107022, 3,8,9,10-tetrahydroxy-pyrano[3,2-c][2]benzopyran-2,6-dione
Application: LDH inhibitor
CAS 568-80-9
MW: 278.2 D
From 50.00€ *
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