37 products were found matching "K00006"!

Adipostatin A is an inhibitor of glycerol-3-phosphate dehydrogenase (GPDH, IC50 = 4.1 µM). It prevents triglyceride accumulation in 3T3-L1 cells when applied at 5-7.5 µM. Adipostatin A is cytotoxic against fibroblast carcinoma KB cell lines with an IC50 value of 10.6 µM.Formal Name: 5-pentadecyl-1,3-benzenediol. CAS...

Ginkgoneolic acid is an anacardic acid and analog of anacardic acid monoene (Cay-18422) originally isolated from G. biloba and has diverse biological activities. It inhibits glycerol-3-phosphate dehydrogenase (GPDH, IC50 = 3 µg/ml). Ginkgoneolic acid inhibits PI3Kdelta (IC50 = 2.49 µM) and IgE-mediated RBL-2H3 mast...

The protein encoded by this gene catalyzes the conversion of sn-glycerol 3-phosphate to glycerone phosphate. The encoded protein is found in the cytoplasm, associated with the plasma membrane, where it binds the sodium channel, voltage-gated, type V, alpha subunit (SCN5A). Defects in this gene are a cause of Brugada...

Protein function: Plays a role in regulating cardiac sodium current, decreased enzymatic activity with resulting increased levels of glycerol 3-phosphate activating the DPD1L-dependent SCN5A phosphorylation pathway, may ultimately lead to decreased sodium current, cardiac sodium current may also be reduced due to...

Human GPD1 (glycerol-3-phosphate dehydrogenase 1), also known as GPDH1, GenBank Accession No. NM_005276, amino acids 2-349(end), with N-terminal His-tag, MW=38.4 kDa, expressed in an E. coli expression system.

This gene encodes a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family. The encoded protein plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of dihydroxyacetone phosphate (DHAP) and reduced nicotine adenine dinucleotide (NADH) to...

WB 1:500 - 1:2000. Protein function: Plays a role in regulating cardiac sodium current, decreased enzymatic activity with resulting increased levels of glycerol 3-phosphate activating the DPD1L-dependent SCN5A phosphorylation pathway, may ultimately lead to decreased sodium current, cardiac sodium current may also...

The protein encoded by this gene catalyzes the conversion of sn-glycerol 3-phosphate to glycerone phosphate. The encoded protein is found in the cytoplasm, associated with the plasma membrane, where it binds the sodium channel, voltage-gated, type V, alpha subunit (SCN5A). Defects in this gene are a cause of Brugada...

This gene encodes a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family. The encoded protein plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of dihydroxyacetone phosphate (DHAP) and reduced nicotine adenine dinucleotide (NADH) to...