10 products were found matching "GeneID 8505"!

The Enzolution(R) PARG Assay System is intended for use with the Transcreener(R) ADPR FP Assay Kit (Part #3030) to measure enzymatic activity for PARG (poly(ADP-ribose) glycohydrolase). PARG produces ADPR from the breakdown of poly(ADP-ribose) (polyADPR). It plays an important role in DNA damage repair and has been...

Active, full-length (aa 1-976), human poly(ADP-Ribose) glycohydrolase (PARG) enzyme, C-terminal 6xHis-tagged protein expressed and purified from Baculovirus-infected insect cells. The enzyme has been thoroughly validated with Transcreener ADPR Activity Assays. For specific activity, please refer to the Certificate...

Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. PARG antibody detects Poly(ADP-ribose) glycohydrolase, encoded by the PARG gene on chromosome 10q11.23. PARG antibody is widely used in DNA damage response, chromatin remodeling, and cancer biology research. PARG is the main enzyme responsible...

Protein function: Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase (PubMed:23102699). PARG acts both as an endo- and exoglycosidase, releasing PAR of different length as well as ADP- ribose monomers (PubMed:23102699). Required for...

Protein function: Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase (PubMed:23102699). PARG acts both as an endo- and exoglycosidase, releasing PAR of different length as well as ADP- ribose monomers (PubMed:23102699). Required for...

Human PARG is fused to a His-tag. Liquid. In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride, 0.2% NP-40, 50mM imidazole and 10% glycerol. Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase. PARG hydrolyzes poly(ADP-ribose) at...

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....

Poly(ADP-ribose) glycohydrolase (PARG) is the major enzyme responsible for the catabolism of poly(ADP-ribose), a reversible covalent-modifier of chromosomal proteins. The protein is found in many tissues and may be subject to proteolysis generating smaller, active products. Applications: Suitable for use in Western...

Poly(ADP-ribose) glycohydrolase (PARG) is the major enzyme responsible for the catabolism of poly(ADP-ribose), a reversible covalent-modifier of chromosomal proteins. The protein is found in many tissues and may be subject to proteolysis generating smaller, active products. Applications: Suitable for use in ELISA,...

Poly(ADP-ribose) glycohydrolase (PARG) is the major enzyme responsible for the catabolism of poly(ADP-ribose), a reversible covalent-modifier of chromosomal proteins. The protein is found in many tissues and may be subject to proteolysis generating smaller, active products. Applications: Suitable for use in ELISA...