124 products were found matching "GeneID 841"!

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Caspase 8 is also known as CAP4, MACH or MCH5. The CASP8 gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive...

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of...

This kits makes use of a cell-permeant green fluorecent probe (FAM-LETD-FMK ) that binds to active caspase-8 in living cells undergoing apoptosis. Excitation wavelength 488-492nm, emission 515-535nm.

Caspase-8 is an initiator caspase with roles in cell death, including induction of apoptosis and pyroptosis and inhibition of necroptosis. It is widely expressed during development and adulthood with high levels of expression in the heart and limb buds, as well as other tissues, in development and in leukocytes in...

Recognizes the p18 subunit of human caspase-8. Liquid. Purified from concentrated hybridoma tissue culture supernatant. Procaspase-8 belongs to the family of caspases. Binding of FasL to Fas leads to formation of a receptor complex at the cellular membrane, which was named DISC. The DISC consists of oligomerized...

The Homogeneous Caspase-8 Assay Kit is a complete assay system designed to measure Caspase-8 activity for screening and profiling applications. It comes in a convenient 96-well format, with all the reagents necessary for 100 fluorescent Caspase-8 activity measurements. In addition, the kit includes purified...

Anti-Caspase-8 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Depending on cell lines or tissues used, either full-length or other cleavage products may be observed. Protein function: Most upstream protease of the activation cascade of caspases responsible for the...

Ex: 534 nm. Em: 619 nm. Soluble in: DMSO. ProRedT-derived protease substrates are colorless and non-fluorescent. Cleavage of blocking protease-cleavable peptide residue by caspases generates the strongly red fluorescent ProRedT that can be monitored fluorimetrically at ~620 nm with excitation of ~530 nm....

Our Cell Meter(TM) assay kits are a set of tools for monitoring cellular functions. There are a variety of parameters that can be used to monitor cell apoptosis. This particular kit is designed to monitor cell apoptosis by measuring caspase 8 activity. Caspase 8 is a caspase protein, encoded by the CASP8 gene....

Protein function: Most upstream protease of the activation cascade of caspases responsible for the TNFRSF6/FAS mediated and TNFRSF1A induced cell death. Binding to the adapter molecule FADD recruits it to either receptor. The resulting aggregate called death- inducing signaling complex (DISC) performs CASP8...

Anti-Caspase-8 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Anti-Caspase-8 from Chimpanzee, Human, Rhesus Monkey and Mouse based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-Caspase-8 from other sources has not been...