163 products were found matching "GeneID 5443"!

This gene encodes a preproprotein that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the preproprotein and, depending on tissue type and the available convertases, processing...

ACTH, adrenocorticotropic hormone, is a peptide hormone cleavage product of the POMC protein produced by the pituitary gland. ACTH plays an important role in stress and circadian rhythm signaling. Its primary action is on the adrenal cortex, where its binding induces the secretion of glucocorticoid steroid hormones....

Protein function: Corticotropin: Stimulates the adrenal glands to release cortisol. [The UniProt Consortium]

Protein function: Corticotropin: Stimulates the adrenal glands to release cortisol. [The UniProt Consortium]

ACTH (1-39) is a potent agonist of melanocortin receptor 2 (MC2R) with an EC50 value of 57 pM in HeLa cells expressing the mouse receptor. It induces accumulation of cAMP and release of corticosterone from rat adrenal cells in a concentration-dependent manner. ACTH (1-39) also protects neurons from death induced by...

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide.

beta-Endorphin is an endogenous 31-amino acid neuropeptide and opioid receptor agonist that binds to µ-, delta-, and kappa-opioid receptors (Kis = 3.73, 5.02, and 32.7 nM, respectively, in COS-1 cells expressing rat receptors). It binds to rat and mouse brain membrane preparations (IC50s = 0.33 and 0.67 nM,...

Protein function: ACTH stimulates the adrenal glands to release cortisol. [The UniProt Consortium]

Protein function: ACTH stimulates the adrenal glands to release cortisol. [The UniProt Consortium]

Protein function: ACTH stimulates the adrenal glands to release cortisol. [The UniProt Consortium]

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Adrenocorticotropic hormone (ACTH), also known as Corticotropin, is a polypeptide tropic hormone produced and secreted by the anterior pituitary gland. It is an important component of the hypothalamic-pituitary-adrenal axis and is often produced in response to...