53 products were found matching "GeneID 4615"!

Protein function: Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated...

MyD88 (Myeloid differentiation factor) is an essential adaptor molecule in all TLR (Toll-like receptor) signaling pathways except TLR3. MyD88 is composed of an N-terminal (Death Domain) and a highly conserved C-terminal TIR (Toll/interleukin-1 Receptor) domain. It is found to stimulate IL-1R/IL18R-mediated...

Protein function: Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated...

Protein function: Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated...

Anti-MyD88 Monoclonal Antibody was Protein A purified from monospecific antiserum by immunoaffinity purification. Cross reactivity with MyD88 [2E9C2] from other sources has not been determined. Protein function: Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate...

Anti-MYD88 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with MYD88 from other sources has not been determined. Protein function: Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts...

Natural and recombinant human MyD88. There is no detectable cross-reactivity with other relevant proteins. Protein function: Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation,...

0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. MYD88 (myeloid differentiation primary response 88) is an essential signal transducer in the IL-1R and Toll-like receptor signaling pathways which regulate activation of numerous proinflammatory genes. Activated TLR signaling via MYD88 ultimately leads...

Antibody in PBS with 50% Glycerol, 1% BSA and 0.09% sodium azide. This antibody reacts to the human myeloid differentiation primary response protein MyD88. Protein function: Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2,...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Myeloid differentiation primary response gene 88 is a protein that in humans is encoded by the MYD88 gene. MyD88 is a key downstream adapter for most Toll-like receptors (TLRs) and interleukin-1 receptors(IL1Rs). It a cytosolic adapter protein that plays a...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. MyD88 is a cytosolic adapter protein that plays a central role in theinnateand adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 andToll-like receptorsignaling pathways. Inhibiting the IL1R/MyD88 pathway in...

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Myeloid differentiation primary response gene 88 Protein function: Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via...