110 products were found matching "GeneID 3643"!

Product Description: Insulin receptor (INSR) is a transmembrane receptor tyrosine kinase that plays a central role in mediating the effects of insulin on glucose homeostasis and metabolism. Structurally, the mature receptor is a tetramer composed of two extracellular alpha-subunits, responsible for insulin binding,...

Product Description: Insulin receptor (INSR) is a transmembrane receptor tyrosine kinase that plays a central role in mediating the effects of insulin on glucose homeostasis and metabolism. Structurally, the mature receptor is a tetramer composed of two extracellular alpha-subunits, responsible for insulin binding,...

Product Description: Insulin receptor (INSR) is a transmembrane receptor tyrosine kinase that plays a central role in mediating the effects of insulin on glucose homeostasis and metabolism. Structurally, the mature receptor is a tetramer composed of two extracellular alpha-subunits, responsible for insulin binding,...

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it...

Protein function: Receptor tyrosine kinase which mediates the pleiotropic actions of insulin. Binding of insulin leads to phosphorylation of several intracellular substrates, including, insulin receptor substrates (IRS1, 2, 3, 4), SHC, GAB1, CBL and other signaling intermediates. Each of these phosphorylated...

Protein function: Receptor tyrosine kinase which mediates the pleiotropic actions of insulin. Binding of insulin leads to phosphorylation of several intracellular substrates, including, insulin receptor substrates (IRS1, 2, 3, 4), SHC, GAB1, CBL and other signaling intermediates. Each of these phosphorylated...

Protein function: Receptor tyrosine kinase which mediates the pleiotropic actions of insulin. Binding of insulin leads to phosphorylation of several intracellular substrates, including, insulin receptor substrates (IRS1, 2, 3, 4), SHC, GAB1, CBL and other signaling intermediates. Each of these phosphorylated...

Protein function: Receptor tyrosine kinase which mediates the pleiotropic actions of insulin. Binding of insulin leads to phosphorylation of several intracellular substrates, including, insulin receptor substrates (IRS1, 2, 3, 4), SHC, GAB1, CBL and other signaling intermediates. Each of these phosphorylated...

Protein function: Receptor tyrosine kinase which mediates the pleiotropic actions of insulin. Binding of insulin leads to phosphorylation of several intracellular substrates, including, insulin receptor substrates (IRS1, 2, 3, 4), SHC, GAB1, CBL and other signaling intermediates. Each of these phosphorylated...

Active human receptor (INSR) (GenBank Accession No. NM_001079817) (amino acids 999-end) with N-terminal GST tag, MW=67 kDa. Expressed in a baculovirus expression system. Assay condition: The enzyme reaction was carried out for 1h at room temperature in a buffer containing 50 mM HEPES (pH7.5), 10 mM MgCl2, 1 mM EDTA,...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. INSR (Insulin Receptor) is a tetramer of two alpha and two beta subunits that are coded by a single gene and are joined by disulfide bonds, a mechanism parallel to that of its ligand, insulin. It belongs to the large class of tyrosine kinase receptors. The...