115 products were found matching "GeneID 2146"!

EZH2(enhancer of zeste 2 polycomb repressive complex 2 subunit) Homo sapiens This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This...

In 1X PBS, pH 7.4, with 0.09% sodium azide. EZH2, SUZ12, and EED form a complex that methylates nucleosomal histone H3 at Lys27. EZH2 contains a SET domain, a signature motif for all known histone lysine methyltransferases except the H3-K79 methyltransferase DOT1, and is therefore likely to be the catalytic subunit....

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Enhancer of zeste homolog 2 (EZH2) is a histone-lysine N-methyltransferase enzyme encoded by EZH2gene. It is mapped to 7q36.1. This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved...

The EZH2/EED/SUZ12/RbAp48/AEBP2 Direct Activity Assay kit is designed to measure EZH2/EED/SUZ12/RbAp48/AEBP2 activity using purified enzyme complex or EZH2/EED/SUZ12/RbAp48/AEBP2 extracts. The EZH2/EED/SUZ12/RbAp48/AEBP2 Direct Activity Assay Kit comes in a convenient format, with a 96-well plate precoated with...

Protein function: Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys- 27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1,...

Human EZH2 (GenBank Accession No. NM_004456), (amino acids 2-end) with N-terminal His-GST tag, MW= 114 kDa, expressed in a Sf9 baculovirus expression system.

Active complex of human EZH2 (GenBank Accession No. NM_004456), (amino acids 2-end) with N-terminal His tag, MW= 86 kDa, human EED (GenBank Accession No. NM_003797) (amino acid 2-end) with N-terminal Flag tag, MW= 51 kDa, and human SUZ12 (GenBank Accession No. NM_015355) (amino-acids 2-end) with N-terminal His tag,...

Active complex of human EZH2, GenBank Accession No. NM_004456, amino acids 2-end, with N-terminal His tag, MW= 86 kDa, human EED, NM_003797, a-a 2-end, with N-terminal DDDDK tag (FLAG), MW= 51 kDa, human SUZ12, NM_015355, a-a 2-end, with N-terminal His tag, MW = 87 kDa, Human AEBP2, NM_153207, a-a 2-end, with...

Active complex of human EZH1, GenBank Accession No. NM_001991, amino acids 2-end, with N-terminal His tag, MW= 86 kDa, human EED, NM_003797, a-a 2-end, with N-terminal DDDDK tag (FLAG), MW= 51 kDa, human SUZ12, NM_015355, a-a 2-end, with N-terminal His tag, MW = 87 kDa.

Complex of human EZH2 (GenBank Accession No. NM_004456), (a.a. 2-end) with N-terminal His-tag, MW= 86 kDa, human EED (NM_003797) (a.a. 2-end) with N-terminal Flag tag, MW= 51 kDa, human SUZ12 (NM_015355) (a.a. 2-end) with N-terminal His tag, MW = 87 kDa

Protein function: Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys- 27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1,...

Protein function: Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys- 27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1,...