Description: Frizzled 5 Protein, Mouse, Recombinant (hFc) is expressed in CHO mammalian cells with hFc tag. The predicted molecular weight is 42.9 kDa and the accession number is Q9EQD0.

Protein function: Receptor for Wnt proteins (PubMed:11092808, PubMed:18230341). Can activate WNT2, WNT10B, WNT5A, but not WNT2B or WNT4 (in vitro), the in vivo situation may be different since not all of these are known to be coexpressed (PubMed:11092808). In neurons, activation of WNT7A promotes formation of...

Description: Frizzled 5 Protein, Mouse, Recombinant (hFc) is expressed in CHO mammalian cells with hFc tag. The predicted molecular weight is 42.9 kDa and the accession number is Q9EQD0.

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....

Protein function: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK- 3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway...