In 1X PBS pH 7.4 with 0.09% sodium azide. Nlrp6 may mediate activation of CASP1 via ASC and promote activation of NF-kappa-B (By similarity). Protein function: Acts as the sensor component of the NLRP6 inflammasome, which mediates inflammasome activation in response to various pathogen- associated signals, leading...

NOD-like receptor family pyrin domain containing 6 (NLRP6), a member of the NOD-like receptor (NLR) family, migrating at 100 kDa in western blot, acts as a cytosolic innate immune sensor that recognizes microbe-associated molecular patterns. NLRP6 recruits the adaptor apoptosis-associated speck-like protein (ASC)...

Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...

Nlrp6 may mediate activation of CASP1 via ASC and promote activation of NF-kappa-B (By similarity). Applications: Suitable for use in Western Blot, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing...