40 products were found matching "GeneID 10038"!

Active, full-length human PARP2 (AA 1-583) protein expressed and purified from Baculovirus infected insect cells with an N-Terminal His tag. The enzyme has been thoroughly validated with the Transcreener pADPr Assay Kit. For specific activity, please refer to the Certificate of Analysis for each individual enzyme...

The Enzolution(R) PARP2 Assay System is intended for use with the Transcreener(R) pADPr PARP Assay Kits (Parts #3043 and #3044) to measure the enzymatic activity of PARP2 (poly(ADP-ribose)polymerase 2). Upon binding to DNA, PARP2 forms poly(ADP-ribose) (pADPr) chains on target proteins, including itself, using NAD+...

The Enzolution(R) PARP2 Assay System is intended for use with the Transcreener(R) pADPr PARP Assay Kits (Parts #3043 and #3044) to measure the enzymatic activity of PARP2 (poly(ADP-ribose)polymerase 2). Upon binding to DNA, PARP2 forms poly(ADP-ribose) (pADPr) chains on target proteins, including itself, using NAD+...

Active human PARP2 (GenBank Accession No. NM_005484), amino-acids 2-583 with N-terminal GST tag, MW = 92 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

Protein function: Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism (PubMed:10364231, PubMed:28190768). This modification follows DNA damages and appears as an obligatory step...

Protein function: Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway...

The PARP2 Colorimetric Activity Assay Kit is designed to measure PARP2 activity for screening and profiling applications. PARP2 is known to catalyze the NADdependent addition of poly(ADP-ribose) to histones. The key to the PARP2 Colorimetric Activity Assay is the biotinylated substrate. With this kit, only three...

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Poly (ADP-ribose) polymerase family, member 2 Protein function: Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor...

Protein function: Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair (PubMed:10364231, PubMed:28190768, PubMed:25043379). Mainly mediates glutamate and aspartate ADP-ribosylation of target proteins: the ADP-D- ribosyl group of NAD(+) is transferred to the...

Poly(ADP-Ribose) polymerase 2 (PARP2) is an ADP-ribosylating enzyme with a role in the DNA damage response (DRR). It is composed of a natively disordered N-terminal region containing a nuclear localization sequence, a central Trp-Gly-Arg (WGR) domain that is essential to DNA damage-dependent catalytic domain...

The PARPtrap(TM) Assay Kit for PARP2 is designed to measure PARP2/DNA complex formation in a high throughput screening assay using fluorescence polarization (FP). Similarly, to PARP1, PARP2 recognizes and binds damaged DNA via its DNA-binding domain. Binding to DNA activates PARP2 and in the presence of NAD+ PARP2...

Protein function: Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair (PubMed:10364231, PubMed:28190768, PubMed:25043379). Mainly mediates glutamate and aspartate ADP-ribosylation of target proteins: the ADP-D- ribosyl group of NAD(+) is transferred to the...