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Item number: Cay17290-1

IMD 0354 is an IKKbeta (IKK2) inhibitor that blocks NF-kappaB phosphorylation (IC50 = ~250 nM) and subsequent NF-kappaB p65 nuclear translocation. It exhibits cardioprotective properties by decreasing expression of P-selectin and ICAM-1 in the vasculature and blocking cardiomyocyte IL-1beta and MCP-1 production,...

Keywords:	IKK2 Inhibitor V, N-[3,5-bis(trifluoromethyl)phenyl]-5-chloro-2-hydroxy-benzamide
Application:	IKK2 inhibitor
CAS	978-62-1
MW:	383.7 D

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