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Item number: Cay43165-10

An inhibitor of topoisomerase II (IC50 = 20 µM) and xanthine oxidoreductase (IC50 = 51 µM), selective for topoisomerase II over topoisomerase I (IC50 = ~200 µM), increases lifespan in a variety of murine cancer models, including B16 melanoma, L1210 leukemia, P388 leukemia, and M5076 sarcoma models. Formulation: A...

Keywords:	NSC 336628, RLBN 1001, hexahydro-4,6-dioxo-N-phenyl-2-thioxo-5-pyrimidinecarboxamide
Application:	Topoisomerase II / xanthine oxidoreductase inhibitor
CAS	97534-21-9
MW:	263.27 D

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