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Item number: Cay28779-10

AMN082 is an orally bioavailable allosteric agonist of metabotropic glutamate receptor 7 (mGluR7). It inhibits cAMP accumulation induced by forskolin in CHO cells expressing human mGluR7b (EC50 = 64 nM). AMN082 (10 µM) is selective for mGluR7a and mGluR7b over mGluR1b, mGluR4, and mGluR8a with 140, 90, 15, 18, and...

Keywords:	N,N'-bis(diphenylmethyl)-1,2-ethanediamine, dihydrochloride
Application:	Allosteric mGluR7 antagonist
CAS	97075-46-2
MW:	465.5 D

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