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Item number: Cay19915-5

Daprodustat is an inhibitor of hypoxia-inducible factor prolyl hydroxylase 1 (HIF-PH1), HIF-PH2, and HIF-PH3 (IC50s = 3.5, 22.2, 5.5 nM, respectively). It is selective for HIF-PH1, -2, and -3 over factor-inhibiting HIF (FIH) and collagen prolyl hydroxylase (CP4H, IC50s = 9,800 and >200,000 nM, respectively)....

Keywords:	GSK1278863, N-[(1,3-dicyclohexylhexahydro-2,4,6-trioxo-5-pyrimidinyl)carbonyl]-glycine
Application:	HIF-prolyl hydroxylase inhibitor
CAS	960539-70-2
MW:	393.4 D

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