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BI605906
BI605906

Item number: TGM-T14567-100mg

Description: BI605906 is an IKKbeta inhibitor that inhibits tumor necrosis factor alpha-dependent IkappaB degradation and expression of the pro-inflammatory mediator interleukin-6, which can be used to study inflammatory skin diseases such as psoriasis. Target: IkappaB/IKK, IL Receptor. Smiles:...
Keywords: BI 605906, BI-605906
Application: IKK beta inhibitor
CAS 960293-88-3
MW: 432.51 D
From 31.00€ *
Review
BI-605906
BI-605906

Item number: Cay19184-1

BI-605906 is an inhibitor of inhibitor of kappa B kinase subunit beta (IKKbeta, IC50 = 380 nM). It is selective for IKKbeta over insulin-like growth factor 1 (IGF1, IC50 = 7.6 µM) and over 100 kinases in a panel up to 10 µM. BI-605906 partially inhibits IL-1-stimulated activation of IKKepsilon/TBK1 in vitro....
Keywords: 3-amino-4-(1,1-difluoropropyl)-6-[4-(methylsulfonyl)-1-piperidinyl]-thieno[2,3-b]pyridine-2-carboxamide
Application: IKK beta inhibitor
CAS 960293-88-3
MW: 432.5 D
From 104.00€ *
Review