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NIH 12848
NIH 12848

Item number: Cay26035-1

NIH 12848 is an inhibitor of phosphatidylinositol 5-phosphate 4-kinase gamma (PI5P4Kgamma, IC50 = ~1 µM). It is selective for PI5P4Kgamma over PI5P4Kalpha and PI5P4Kbeta (IC50s = >100 µM). NIH 12848 inhibits translocation of the Na+/K+-ATPase to the plasma membrane in mouse principal kidney cortical collecting duct...
Keywords: N-(2-thienylmethyl)-2-[2-(trifluoromethyl)phenyl]-4-quinazolinamine
Application: PIP4K2C inhibitor
CAS 959551-10-1
MW: 385.4 D
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