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Item number: AG-CN2-0035-C050

Isolated from marine sponge Theonella swinhoei. Cell permeable dimeric dilactone macrolide - Cytotoxic compound - Specific actin filament (F-actin) inhibitor - Disrupts the actin cytoskeleton by sequestering actin dimers and rapidly severing actin filaments (F-actin) - Depolymerizes actin filaments (F-actin) -...

Application:	F-actin depolymerization
CAS	95927-67-6
MW:	1389,9 D

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Swinholide A

Item number: Cay19611-50

Swinholide A is a natural dimeric dilactone macrolide toxin that causes actin depolymerization in cells. It stabilizes actin dimers and also binds to and severs F-actin filaments. Swinholide A binds to G-actin in a 1:2 molar ratio and decreases the rate of nucleotide exchange in G-actin.Formal Name:...

Keywords:	(1R,3S,5E,7E,11S,12S,13R,15S,16S,17S,19S,23R,25S,27E,29E,33S,34S,35R,37S,38S,39S,41S)-3,13,15,25,35,37-hexahydroxy-11,33-b...
Application:	Actin depolymerization
CAS	95927-67-6
MW:	1389.9 D

From 179.00€ *

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