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Item number: TGM-T8965-10mg

Description: VK-II-86 is a non-beta-blocking carvedilol analog. It prevents ouabain-Induced cardiotoxicity. Target: Others. Smiles: COc1ccccc1OCCNCC(O)CCOc1cccc2[nH]c3ccccc3c12. References: Gonano L A , Sepúlveda, Marisa, Morell M , et al. Non-beta-Blocking Carvedilol Analog, VK-II-86, Prevents Ouabain-Induced...

Application:	SOICR inhibitor
CAS	955371-84-3
MW:	420.5 D

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VK-II-86

Item number: Cay36677-1

VK-II-86 is an inhibitor of store-overload-induced calcium release (SOICR) and a derivative of carvedilol (Cay-15418). It inhibits SOICR in HEK293 cells expressing the ryanodine receptor 2 (RyR2) R4496C (RyR2R4496C) mutation (IC50 = 16.8 µM), a mutation that results in spontaneous calcium release from the...

Keywords:	4-(9H-carbazol-4-yloxy)-1-[[2-(2-methoxyphenoxy)ethyl]amino]-2-butanol
Application:	SOICR inhibitor
CAS	955371-84-3
MW:	420.5 D

From 49.00€ *

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