4 products were found matching "950769-58-1"!
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Quizartinib
Item number: Cay17986-1
Quizartinib is an inhibitor of FMS-related tyrosine kinase 3 (FLT3, Kd = 1.6 nM) and demonstrates high selectivity for FLT3 when tested against a panel of 227 additional kinases. It inhibits the proliferation of the human leukemia cell line MV4-11, which harbors a homozygous FLT3-ITD mutation, with an IC50 value of...
| Keywords: | AC220, N-[5-(1,1-dimethylethyl)-3-isoxazolyl]-N'-[4-[7-[2-(4-morpholinyl)ethoxy]imidazo[2,1-b]benzothiazol-2-yl]phenyl]-urea |
| Application: | FLT3 inhibitor |
| CAS | 950769-58-1 |
| MW: | 560.7 D |
From 44.00€
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Quizartinib
Item number: LKT-Q8139.10
A uniquely potent and selective inhibitor of the receptor tyrosine kinase FLT3.
| Keywords: | AC220 |
| CAS | 950769-58-1 |
| MW: | 560.67 D |
From 283.00€
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Quizartinib
Item number: SYN-1003-M001
Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. Quizartinib (AC220) is a second-generation FLT3 inhibitor that has shown promising activity in AML in Phase II clinical trials. It inhibits mutant and wild-type FLT3 in vivo at 0.1 and 0.5µM, respectively, and has shown favorable activity and tolerability in...
| Keywords: | AC220 |
| Application: | FLT3 inhibitor |
| CAS | 950769-58-1 |
| MW: | 560,7 D |
From 139.00€
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Quizartinib
Item number: TGM-T2066-100mg
Description: Quizartinib (AC220) is an inhibitor of FLT3 (Kd: 1.6 nM) and demonstrates high selectivity for FLT3 when tested against a panel of 227 additional kinases. Target: FLT, Autophagy, Apoptosis, Ligands for Target Protein for PROTAC. Smiles:...
| Keywords: | AC220 |
| CAS | 950769-58-1 |
| MW: | 560.67 D |
From 50.00€
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