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WWL113
Item number: Cay16181-1
Mouse carboxylesterase 3 (Ces3, also named Ces 1d) mediates triglyceride hydrolysis in white adipose tissue, liberating free fatty acids into circulation. Although important for basal lipolysis, Ces3 expression can be induced by xenobiotics. Ces3 activity is significantly elevated during adipocyte differentiation....
| Keywords: | 4'-[[[methyl[[3-(4-pyridinyl)phenyl]methyl]amino]carbonyl]oxy]-[1,1'-biphenyl]-4-carboxylic acid, ethyl ester |
| Application: | mCes3 / hCES1 inhibitor |
| CAS | 947669-86-5 |
| MW: | 466.5 D |
From 56.00€
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WWL113
Item number: TGM-T17259-2mg
Description: WWL113 is a selective and orally active inhibitor of Ces3 (IC50: 120 nM) and Ces1f (IC50: 100 nM), exhibiting excellent selectivity for the 60-kDa serine hydrolase. Target: Others. Smiles: CCOC(=O)c1ccc(cc1)-c1ccc(OC(=O)N(C)Cc2cccc(c2)-c2ccncc2)cc1
| Application: | mCes3 / hCES1 inhibitor |
| CAS | 947669-86-5 |
| MW: | 466.53 D |
48.00€
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