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Item number: Cay18774-5

LY2409881 is a selective inhibitor of IkappaB kinase beta (IKK2, IC50 = 30 nM). It inhibits IKK1 and other common kinases at >10-fold higher concentrations. LY2409881 has been shown to suppress constitutively activated NF-kappaB and to induce apoptosis in lymphoma cells both in vitro and in preclinical mouse models...

Keywords:	2-[5-chloro-2-[[3-(4-methyl-1-piperazinyl)propyl]amino]-4-pyrimidinyl]-N-cyclopropyl-benzo[b]thiophene-4-carboxamide,...
Application:	IKK2 inhibitor
CAS	946518-60-1
MW:	594.4 D

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