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LY2409881
Item number: Cay18774-5
LY2409881 is a selective inhibitor of IkappaB kinase beta (IKK2, IC50 = 30 nM). It inhibits IKK1 and other common kinases at >10-fold higher concentrations. LY2409881 has been shown to suppress constitutively activated NF-kappaB and to induce apoptosis in lymphoma cells both in vitro and in preclinical mouse models...
| Keywords: | 2-[5-chloro-2-[[3-(4-methyl-1-piperazinyl)propyl]amino]-4-pyrimidinyl]-N-cyclopropyl-benzo[b]thiophene-4-carboxamide,... |
| Application: | IKK2 inhibitor |
| CAS | 946518-60-1 |
| MW: | 594.4 D |
From 51.00€
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LY2409881 trihydrochloride
Item number: TGM-T2081-100mg
Description: LY2409881 trihydrochloride is a novel specific inhibitor of IKK2 (IC50: 30 nM), IC50 for IKK1 and other common kinases is at least one log higher. Target: IkappaB/IKK, Apoptosis. Smiles: Cl.Cl.Cl.CN1CCN(CCCNc2ncc(Cl)c(n2)-c2cc3c(cccc3s2)C(=O)NC2CC2)CC1. References: Deng C, et al. Clin Cancer Res. 2015,...
| Keywords: | LY2409881 |
| CAS | 946518-60-1 |
| MW: | 594.43 D |
From 30.00€
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