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RN-1734
Item number: Cay24205-5
RN-1734 is a transient receptor potential vanilloid 4 (TRPV4) antagonist, blocking calcium influx induced by the TRPV4 agonist 4alpha-phorbol 12,13-didecanoate (Cay-20446) with IC50 values of 2.3, 5.9, and 3.2 µM for human, mouse, and rat TRPV4, respectively. It is selective for TRPV4 over TRPV1, TRPV3, and TRPM8...
| Keywords: | 2,4-dichloro-N-(1-methylethyl)-N-[2-[(1-methylethyl)amino]ethyl]-benzenesulfonamide |
| Application: | TRPV4 antagonist |
| CAS | 946387-07-1 |
| MW: | 353.3 D |
From 92.00€
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RN-1734
Item number: TGM-T7572-100mg
Description: RN-1734 is selective TRPV4 channel antagonist(IC50 of 2.3 µM,5.9 µM,3.2 µM for hTRPV4, mTRPV4 and rTRPV4,respectively). Target: TRP/TRPV Channel. Smiles: S(N(CCNC(C)C)C(C)C)(=O)(=O)C1=C(Cl)C=C(Cl)C=C1. References: Kato K , Morita I . Acidosis environment promotes osteoclast formation by acting on the...
| Application: | TRPV4 antagonist |
| CAS | 946387-07-1 |
| MW: | 353.31 D |
From 29.00€
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