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Item number: TGM-T16114-100mg

Description: Pavinetant (MLE-4901) is an orally available neurokinin-3 receptor (NK3R) antagonist used to improve menopausal symptoms. Target: Neurokinin receptor. Smiles: CC[C@H](NC(=O)c1c(NS(C)(=O)=O)c(nc2ccccc12)-c1ccccc1)c1ccccc1. References: Li Y, et al. In vitro assessment of metabolic drug-drug interaction...

Keywords:	AZD2624, MLE-4901, AZD4901
Application:	Targets tachykinin receptor 3 (TACR3)
CAS	941690-55-7
MW:	459.56 D

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MLE-4901

Item number: Cay23587-1

MLE-4901 is an antagonist of the neurokinin-3 (NK3) receptor. It inhibits human liver microsomal CYP3A4/5 with apparent IC50 values of 7.1 and 19.8 µM in midazolam 1'-hydroxylation and testosterone 6beta-hydroxylation assays, respectively.Formal Name:...

Keywords:	AZD 2624, AZD 4901, 3-[(methylsulfonyl)amino]-2-phenyl-N-[(1S)-1-phenylpropyl]-4-quinolinecarboxamide
Application:	Neurokinin-3 (NK3) receptor antagonist
CAS	941690-55-7
MW:	459.6 D

From 94.00€ *

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