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PKM2-IN-1
Item number: TGM-T4170-100mg
Description: PKM2-IN-1 (compound 3k) exhibits inhibitory activity against PKM2 with an IC50 of 2.95 µM, while the IC50 for PKM1 is 4-5 times higher. Target: PKM. Smiles: CC1=C(CSC(=S)N2CCCCC2)C(=O)c2ccccc2C1=O. References: Ning X, et al. Discovery of novel naphthoquinone derivatives as inhibitors of the tumor cell...
| Keywords: | PKM2 inhibitor, compound 3k |
| Application: | PKM2 inhibitor |
| CAS | 94164-88-2 |
| MW: | 345.48 D |
From 34.00€
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PKM2 Inhibitor
Item number: Cay36815-100
PKM2 inhibitor is an inhibitor of pyruvate kinase M2 (PKM2, IC50 = 2.95 µM), a tumor-specific kinase with a role in glycolysis. It is selective for PKM2 over PKM1 and L-type pyruvate kinase (PKLR, IC50s = 16.71 and 8.2 µM, respectively). PKM2 inhibitor is cytotoxic to HCT116, HeLa, and H1299 cells (IC50s = 0.18,...
| Keywords: | Compound 3K, MDK4882, PKM2-IN-1, Pyruvate Kinase M2 Inhibitor, 1-piperidinecarbodithioic acid,... |
| Application: | PKM2 inhibitor |
| CAS | 94164-88-2 |
| MW: | 345.5 D |
From 199.00€
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