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Item number: Cay18384-1

SB-743921 is a potent inhibitor of the kinesin spindle protein Eg5 (Ki = 0.5 nM for microtubule-stimulated ATPase activity). It inhibits the growth of HCT116 colon, LNCaP and PC3 prostate, K562 leukemia, BxPC-3 pancreas, and NCI-H1299 lung cancer cell lines in vitro (GI50s = 25, 22, 48, 50, 80, and 82 nM,...

Keywords:	N-(3-aminopropyl)-N-[(1R)-1-[7-chloro-4-oxo-3-(phenylmethyl)-4H-1-benzopyran-2-yl]-2-methylpropyl]-4-methyl-benzamide,...
Application:	KIF11 inhibitor
CAS	940929-33-9
MW:	553.5 D

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SB-743921 hydrochloride

Item number: TGM-T2255-100mg

Description: SB-743921 hydrochloride (SB743921 HCl) is an effective inhibitor of kinesin spindle protein, KSP, (Ki =0.1 nM). Target: Kinesin, KSP. Smiles: Cl.CC(C)[C@@H](N(CCCN)C(=O)c1ccc(C)cc1)c1oc2cc(Cl)ccc2c(=O)c1Cc1ccccc1. References: Jackson JR, et al. AACR, 2006, Abst 0906.

Keywords:	SB743921 HCl, SB743921
Application:	KIF11 inhibitor
CAS	940929-33-9
MW:	553.52 D

From 37.00€ *

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