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PF-562271 (besylate)
PF-562271 (besylate)

Item number: Cay18499-1

Focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2) are non-receptor tyrosine kinases that constitute the FAK subfamily and play a vital role in many oncogenic pathways. PF-562271 is an ATP-competitive, reversible inhibitor of FAK (IC50 = 1.5 nM) that demonstrates 10-fold reduced potency for PYK2...
Keywords: N-[3-[[[2-[(2,3-dihydro-2-oxo-1H-indol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]-2-pyridinyl]-N-methyl-m...
Application: FAK inhibitor
CAS 939791-38-5
MW: 665.7 D
From 56.00€ *
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PF-562271 besylate
PF-562271 besylate

Item number: TGM-T6177-100mg

Description: PF-562271 besylate (PF-00562271 Besylate) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs. Target: CDK, FAK, PYK2. Smiles:...
Keywords: PF-00562271 Besylate
Application: FAK inhibitor
CAS 939791-38-5
MW: 665.66 D
From 31.00€ *
Review