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Item number: Cay13563-1

Isoforms of phospholipase D (PLD) cleave the head group from phospholipids, releasing the second messenger phosphatidic acid (PA), which can produce changes in Ras activation, cell spreading, stress fiber formation, chemotaxis, and membrane vesicle trafficking. FIPI is a derivative of halopemide which potently...

Keywords:	5-Fluoro-2-Indolyl des-Chlorohalopemide,...
Application:	PLD1/PLD2 inhibitor
CAS	939055-18-2
MW:	421.5 D

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FIPI

Item number: TGM-T3580-2mg

Description: FIPI (5-Fluoro-2-indolyl deschlorohalopemide) is a derivative of halopemide which potently inhibits both PLD1 (IC50 = 25 nM) and PLD2 (IC50 = 20 nM), prevents PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis. Target: Phospholipase, Autophagy. Smiles:...

Keywords:	5-Fluoro-2-indolyl deschlorohalopemide
CAS	939055-18-2
MW:	421.47 D

From 40.00€ *

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