3 products were found matching "935888-69-0"!
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Oprozomib
Item number: TGM-T6041-100mg
Description: Oprozomib (PR-047) (ONX 0912) , an inhibitor for CT-L activity of 20S proteasome beta5(IC50=36 nM)/LMP7(IC50=82 nM), is orally bioavailable. Oprozomib also has potential antineoplastic activity. Target: Proteasome, Autophagy. Smiles:...
| Keywords: | PR-047, ONX 0912 |
| Application: | Targets 20S proteasome subunit beta 5 [EC:3.4.25.1] (PSMB5) |
| CAS | 935888-69-0 |
| MW: | 532.61 D |
From 58.00€
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ONX 0912
Item number: Cay16269-1
ONX 0912 is an orally bioavailable proteasome inhibitor. It potently targets the chymotrypsin-like activity of the 20S proteasome subunits beta5 and LMP7 (IC50s = 36 and 82 nM, respectively). ONX 0912 inhibits the growth of multiple myeloma cells at nanomolar concentrations while not decreasing the viability of...
| Keywords: | Oprozomib, PR-047,... |
| Application: | EGFR T790M inhibitor |
| CAS | 935888-69-0 |
| MW: | 532.6 D |
From 85.00€
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![Oprozomib [ONX 0912]](https://www.biomol.com/media/image/91/89/60/AG-CR1-3672-M001_200x200.png "Oprozomib [ONX 0912]")
Oprozomib [ONX 0912]
Item number: AG-CR1-3672-M005
Synthetic. Chemical. CAS: 935888-69-0. Formula: C25H32N4O7S. MW: 532.6. Synthetic. Potent orally bioavailable irreversible proteasome inhibitor. Analog of Carfilzomib (AG-CR1-3669). Targets the chymotrypsin-like beta5 subunit of the constitutive 20S proteasome (IC50=36nM) and the beta5i subunit [LMP7] of the 20S...
| Keywords: | O-Methyl-N-[(2-methyl-5-thiazolyl)carbonyl]-L-seryl-O-methyl-N-[(1S)-2-[(2R)-2-methyl-2-oxiranyl]-2-oxo-1-(phenylmethyl)et... |
| Application: | Proteasome inhibitor |
| CAS | 935888-69-0 |
| MW: | 532,6 D |
From 44.00€
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