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TAK-901
Item number: TGM-T2709-5mg
Description: TAK-901 has been used in trials studying the treatment of Lymphoma, Myelofibrosis, Multiple Myeloma, Myeloid Metaplasia, and Advanced Solid Tumors, among others. Target: JAK, Aurora Kinase, CDK, Src. Smiles: CCS(=O)(=O)c1cccc(c1)-c1cc(C(=O)NC2CCN(C)CC2)c(C)c2[nH]c3ncc(C)cc3c12. References: Pamela...
| Keywords: | TAK901 |
| Application: | Aurora kinase inhibitor |
| CAS | 934541-31-8 |
| MW: | 504.64 D |
From 60.00€
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TAK-901
Item number: Cay23772-1
TAK-901 is a non-selective Aurora kinase inhibitor (IC50s = 3.1, 10, and 4.2 nM for Aurora A, B, and C, respectively). It also inhibits JAK3, c-Src, CLK2, FGR, YES1, LRRK2, FLT3, Fyn, Abl, and FGFR2 (IC50s = 1.2-6.4 nM) and several other kinases. TAK-901 inhibits Aurora kinase complexes with IC50 values of 21 and 15...
| Keywords: | 5-[3-(ethylsulfonyl)phenyl]-3,8-dimethyl-N-(1-methyl-4-piperidinyl)-9H-pyrido[2,3-b]indole-7-carboxamide |
| Application: | Aurora kinase inhibitor |
| CAS | 934541-31-8 |
| MW: | 504.6 D |
From 67.00€
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