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HSP-990
HSP-990

Item number: Cay19149-1

The heat shock proteins (Hsps) act as molecular chaperones. Hsp90 is an abundant protein with roles in protein folding, cell signaling, and cancer. HSP-990 is an Hsp90 inhibitor with IC50 values of 0.6, 0.8, and 8.5 nM for Hsp90alpha, Hsp90beta, and GRP94, respectively. It inhibits the TRAP1 ATPase with an IC50...
Keywords: NVP-HSP990, (7R)-2-amino-7-[4-fluoro-2-(6-methoxy-2-pyridinyl)phenyl]-7,8-dihydro-4-methyl-pyrido[4,3-d]pyrimidin-5(6H)-one
Application: Hsp90 inhibitor
CAS 934343-74-5
MW: 379.4 D
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