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SPA70
Item number: Cay34490-1
SPA70 is a pregnane X receptor (PXR) antagonist (IC50 = 0.51 µM). It is selective for PXR over 10 additional nuclear receptors at concentrations greater than 5 µM, as well as over a panel of 384 kinases at 10 µM. SPA70 (0.1-10 µM) inhibits PXR activation induced by rifampicin (Cay-14423) in HEK293 cells expressing...
| Keywords: | Specific PXR Antagonist 70, 1-(2,5-dimethoxyphenyl)-4-[[4-(1,1-dimethylethyl)phenyl]sulfonyl]-5-methyl-1H-1,2,3-triazole |
| Application: | PXR antagonist |
| CAS | 931314-31-7 |
| MW: | 415.5 D |
From 51.00€
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Specific PXR antagonist 70
Item number: TGM-T41255-100mg
Description: Specific PXR antagonist 70 is a selective pregnane X receptor (PXR) antagonist with an IC50 of 540 nM and Ki of 390 nM for human PCR and enhances the chemosensitivity of cancer cells. Target: Others. Smiles: COC1=CC=C(OC)C(=C1)N1N=NC(=C1C)S(=O)(=O)C1=CC=C(C=C1)C(C)(C)C. References: Chai SC, Lin W, Li Y,...
| Application: | PXR antagonist |
| CAS | 931314-31-7 |
| MW: | 415.51 D |
From 46.00€
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