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Item number: Cay21688-1

DG-051 is a potent, orally bioavailable leukotriene A4 hydrolase (LTA4H) inhibitor (Kd = 25 nM, IC50 = 47 nM), the enzyme that catalyzes the rate-determining step in the synthesis of LTB4 (Cay-20110). However, it also inhibits the aminopeptidase activity of LTA4H with IC50 values of 72 and 150 nM when tested using...

Keywords:	(2S)-2-[[4-(4-chlorophenoxy)phenoxy]methyl]-1-pyrrolidinebutanoic acid, monohydrochloride
Application:	LTA4H inhibitor
CAS	929915-58-2
MW:	426.3 D

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