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Item number: Cay15423-1

LUF6283 is a partial agonist of GPR109A/HCA2 G protein-coupled receptors (Ki = 0.55 µM in a radioligand binding assay). It stimulates [35S]-GTPgammaS binding and increases phosphorylation of ERK in HEK293T cells expressing GPR109A/HCA2 receptors (EC50s = 3.1 and 0.32 µM, respectively). In vivo, LUF6283 (400 mg/kg...

Keywords:	5-butyl-1H-pyrazole-3-carboxylic acid
Application:	GPR109A partial agonist
CAS	92933-48-7
MW:	168.2 D

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