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GSK461364
Item number: Cay18099-1
Polo-like kinases (Plks) are serine/threonine kinases with key roles in cell cycling. GSK461364 is a potent, reversible inhibitor of Plk1 (Ki = 2.2 nM). It is less effective against Plk2 and Plk3 (Kis = 860 and 1,000 nM, respectively) and at least 1,000-fold selective for Plk1 over a panel of 48 other kinases....
| Keywords: | GSK461364A,... |
| Application: | Plk1 inhibitor |
| CAS | 929095-18-1 |
| MW: | 543.6 D |
From 52.00€
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GSK-461364
Item number: LKT-G7241.1
PLK1 inhibitor.
| Application: | PLK1 inhibitor |
| CAS | 929095-18-1 |
| MW: | 543.6 D |
From 177.00€
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GSK461364
Item number: TGM-T6282-100mg
Description: GSK461364 (GSK461364A)(Ki=2.2 nM) inhibits purified Plk1 .The specificity of GSK461364 for Plk1 is more than 1000-fold over Plk2/3. Target: PLK. Smiles: C[C@@H](Oc1cc(sc1C(N)=O)-n1cnc2ccc(CN3CCN(C)CC3)cc12)c1ccccc1C(F)(F)F. References: Gilmartin AG, et al. Cancer Res, 2009, 69(17), 6969-6977.
| Keywords: | GSK461364A |
| Application: | Plk1 inhibitor |
| CAS | 929095-18-1 |
| MW: | 543.6 D |
From 30.00€
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