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Item number: Cay17635-1

Tankyrases (TNKS) are poly-ADP-ribosyltransferases, which cleave NAD+ to produce nicotinamide and ADP-ribose, which is then covalently attached to an acceptor protein in a process known as poly(ADP-ribosyl)ation. MN-64 is a potent inhibitor of TNKS1 and TNKS2 (IC50s = 6 and 72 nM, respectively). It is ineffective...

Keywords:	2-[4-(1-methylethyl)phenyl]-4H-1-benzopyran-4-one
Application:	TNKS1 / TNKS2 inhibitor
CAS	92831-11-3
MW:	264.3 D

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