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Item number: Cay17971-5

TFC 007 is an inhibitor of hematopoietic prostaglandin D synthase (H-PGDS, IC50 = 0.083 µM). It is selective for H-PGDS over lipocalin PGDS (L-PGDS) and microsomal PGE2 synthase (mPGES) at 100 µM. It is also selective for H-PGDS over COX-1, COX-2, 5-lipoxygenase (5-LO), leukotriene C4 (LTC4) synthase, and...

Keywords:	N-[4-[4-(4-morpholinylcarbonyl)-1-piperidinyl]phenyl]-2-phenoxy-5-pyrimidinecarboxamide
Application:	H-PGDS inhibitor
CAS	927878-49-7
MW:	487.6 D

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