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TFC 007
Item number: Cay17971-5
TFC 007 is an inhibitor of hematopoietic prostaglandin D synthase (H-PGDS, IC50 = 0.083 µM). It is selective for H-PGDS over lipocalin PGDS (L-PGDS) and microsomal PGE2 synthase (mPGES) at 100 µM. It is also selective for H-PGDS over COX-1, COX-2, 5-lipoxygenase (5-LO), leukotriene C4 (LTC4) synthase, and...
| Keywords: | N-[4-[4-(4-morpholinylcarbonyl)-1-piperidinyl]phenyl]-2-phenoxy-5-pyrimidinecarboxamide |
| Application: | H-PGDS inhibitor |
| CAS | 927878-49-7 |
| MW: | 487.6 D |
From 58.00€
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TFC-007
Item number: TGM-T24870-10mg
Description: TFC-007 is a selective and efficient hematopoietic prostaglandin D synthase (H-PGDS) inhibitor, suppressing inflammatory factors. It can be used to synthesize H-PGDS degrader PROTAC (H-PGDS)-1 and study cedar pollen-induced guinea pig allergic rhinitis. Target: PGE Synthase, Ligands for Target Protein...
| Keywords: | TFC007 |
| Application: | H-PGDS inhibitor |
| CAS | 927878-49-7 |
| MW: | 487.55 D |
From 60.00€
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