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Item number: Cay22140-1

T5601640 is an inhibitor of LIM kinase 2 (LIMK2) that inhibits LIMK2-mediated cofilin phosphorylation. It reduces the levels of phosphorylated cofilin (p-cofilin) in mouse embryonic fibroblasts (MEF) lacking neurofibromin (Nf1-/-, IC50 = 30 µM), which normally have high levels of p-cofilin. T5601640 (50 µM)...

Keywords:	T56-LIM Kinase Inhibito, T56-LIMKi, 3-methyl-N-[3-[[[3-(trifluoromethyl)phenyl]amino]carbonyl]phenyl]-5-isoxazolecarboxamide
Application:	LIMK2 inhibitor
CAS	924473-59-6
MW:	389.3 D

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