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Item number: Cay30929-1

ABP 688 is a non-competitive antagonist of metabotropic glutamate receptor 5 (mGluR5, Ki = 3.5 nM in a radioligand binding assay using L(tk-) cell membranes expressing human receptors). It is selective for mGluR5 receptors over a panel of CNS G protein-coupled receptors, ion channels, and transporters at 10 µM. ABP...

Keywords:	3-[2-(6-methyl-2-pyridinyl)ethynyl]-2-cyclohexen-1-one, O-methyloxime
Application:	Non-competitive mGluR5 antagonist
CAS	924298-51-1
MW:	240.3 D

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