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ABP688
Item number: TGM-T26520-100mg
Description: ABP688 is a non-competitive and selective mGluR5 antagonist(Ki = 1.7 nM). ABP688 can be used as a PET tracer for clinical imaging. Target: GluR. Smiles: C(#CC=1N=C(C)C=CC1)C2=CC(=NOC)CCC2. References: DeLorenzo C, et al. In vivo ketamine-induced changes in [11C]ABP688 binding to metabotropic glutamate...
| Keywords: | ABP-688, ABP 688 |
| CAS | 924298-51-1 |
| MW: | 240.3 D |
From 31.00€
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ABP 688
Item number: Cay30929-1
ABP 688 is a non-competitive antagonist of metabotropic glutamate receptor 5 (mGluR5, Ki = 3.5 nM in a radioligand binding assay using L(tk-) cell membranes expressing human receptors). It is selective for mGluR5 receptors over a panel of CNS G protein-coupled receptors, ion channels, and transporters at 10 µM. ABP...
| Keywords: | 3-[2-(6-methyl-2-pyridinyl)ethynyl]-2-cyclohexen-1-one, O-methyloxime |
| Application: | Non-competitive mGluR5 antagonist |
| CAS | 924298-51-1 |
| MW: | 240.3 D |
From 44.00€
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