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MF-438
Item number: TGM-T16068-100mg
Description: MF-438 is an effective and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor (EC50: 2.3 nM for rSCD1). Target: Dehydrogenase, Stearoyl-CoA Desaturase (SCD). Smiles: Cc1nnc(s1)-c1ccc(nn1)N1CCC(CC1)Oc1ccccc1C(F)(F)F
| Application: | Stearoyl-CoA desaturase inhibitor |
| CAS | 921605-87-0 |
| MW: | 421.44 D |
From 98.00€
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MF438
Item number: Cay33349-5
MF438 is an inhibitor of stearoyl-CoA desaturase 1 (SCD1, IC50 = 2.3 nM for the rat enzyme), an enzyme that catalyzes the formation of a cis double bond at the ?9 position of stearoyl-CoA to produce oleoyl-CoA. It reduces spheroid formation in NCI H460 and patient-derived non-small cell lung cancer (NSCLC) cells in...
| Keywords: | 3-(5-methyl-1,3,4-thiadiazol-2-yl)-6-[4-[2-(trifluoromethyl)phenoxy]-1-piperidinyl]-pyridazine |
| Application: | Stearoyl-CoA desaturase inhibitor |
| CAS | 921605-87-0 |
| MW: | 421.4 D |
From 44.00€
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