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Item number: Cay23763-10

Bromfenac is an inhibitor of cyclooxygenase 2 (COX-2, IC50 = 6.6 nM) that is selective over COX-1 (IC50 = 210 nM). It inhibits prostaglandin E2 (PGE2, Cay-14010) production in a rabbit model of LPS-induced eye inflammation. Bromfenac also decreases inflammation following cataract removal in dogs when administered as...

Keywords:	AHR 10282B, 2-amino-3-(4-bromobenzoyl)-benzeneacetic acid, monosodium salt
Application:	COX-2 inhibitor
CAS	91714-93-1
MW:	356.2 D

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Bromfenac Sodium

Item number: TGM-T6424-10mg

Description: Bromfenac Sodium (AHR 10282R) is a nonsteroidal anti-inflammatory drug (NSAID), which has anti-inflammatory activity and may block prostaglandin synthesis by inhibiting cyclooxygenase 1 and 2. Target: COX. Smiles: [Na+].NC1=C(C=CC=C1CC([O-])=O)C(=O)C1=CC=C(Br)C=C1. References: Sancilio LF, et al....

Keywords:	AHR 10282B, Bronuck, AHR 10282R
Application:	COX-2 inhibitor
CAS	91714-93-1
MW:	356.15 D

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