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WAY-316606
WAY-316606

Item number: Cay45425-1

An inhibitor of sFRP1 (IC50 = 0.5 µM), increases Wnt signaling in U2OS osteosarcoma cells (EC50 = 0.65 µM), increases total bone area in a murine calvarial organ culture assay at 0.1 nM. SMILES: O=S(C1=CC=CC=C1)(C2=CC=C(C(F)(F)F)C(S(NC3CCNCC3)(=O)=O)=C2)=O. InChi Code:...
Keywords: 5-(phenylsulfonyl)-N-4-piperidinyl-2-(trifluor omethyl)-benzenesulfonamide
Application: sFRP1 inhibitor
CAS 915759-45-4
MW: 448.48 D
From 134.00€ *
Review
WAY-316606
WAY-316606

Item number: Cay26324-1

WAY-316606 is an inhibitor of secreted frizzled-related protein 1 (sFRP1, IC50 = 0.5 µM). It increases Wnt signaling in U2OS osteosarcoma cells (EC50 = 0.65 µM). WAY-316606 increases total bone area in a murine calvarial organ culture assay when used at concentrations greater than 0.1 nM.Formal Name:...
Keywords: 5-(phenylsulfonyl)-N-4-piperidinyl-2-(trifluoromethyl)-benzenesulfonamide
Application: sFRP-1 inhibitor
CAS 915759-45-4
MW: 448.5 D
From 56.00€ *
Review
WAY 316606
WAY 316606

Item number: TGM-T4468-100mg

Description: WAY 316606 is an inhibitor of the secreted protein sFRP-1, an endogenous antagonist of the secreted glycoprotein [Wnt]. Target: Wnt/beta-catenin. Smiles: FC(F)(F)c1ccc(cc1S(=O)(=O)NC1CCNCC1)S(=O)(=O)c1ccccc1. References: Bodine PV, et al. A small molecule inhibitor of the Wnt antagonist secreted...
Application: sFRP-1 inhibitor
CAS 915759-45-4
MW: 448.48 D
From 41.00€ *
Review