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Cot Inhibitor 1
Item number: Cay43368-1
Cot inhibitor 1 is an inhibitor of MAP3K8 (IC50 = 28 nM). It inhibits LPS-induced increases in TNF-alpha levels in isolated human whole blood (IC50 = 5. µM).. Solulibility: DMSO: Soluble: = 10 mg/ml: .
| Keywords: | 8-chloro-4-[(3-chloro-4-fluorophenyl)amino]-6-[[[1-[2-(hexahydro-1H-azepin-1-yl)ethyl]-1H-1,2,3-triazol-4-yl]methyl]amino]... |
| Application: | MAP3K8 (COT) inhibitor |
| CAS | 915365-57-0 |
| MW: | 553.47 D |
From 96.00€
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Cot inhibitor-1
Item number: TGM-T10865-100mg
Description: Cot inhibitor-1 is a selective inhibitor of Cot protein kinase (also known as Tpl2 or MAP3K8) (IC50 at 28 nM). Cot inhibitor-1 inhibited TNF-alpha production in human whole blood with IC50 of 5.7 nM. Cot is involved in a variety of cellular signaling pathways, particularly those involved in inflammation...
| Application: | COT (MAP3K8) inhibitor |
| CAS | 915365-57-0 |
| MW: | 553.46 D |
From 70.00€
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