2 products were found matching "914382-60-8"!

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Item number: Cay43665-1

An inhibitor of HDACs and a prodrug form of CHR-2847, increases intracellular protein acetylation in CD14+ primary human AML cells and gammaH2AX levels in primary CMML cells, selectively inhibits the growth of primary AML cells over normal bone marrow cells at 500 nM, induces beta-oxidation of hexacosanoic acid in...

Keywords:	alphaS-[[[4-[[8-(hydroxyamino)-1,8-dioxooctyl]amino]phenyl]methyl]amino]-benzeneacetic acid, cyclopentyl ester
Application:	HDAC inhibitor, CHR-2847 prodrug
CAS	914382-60-8
MW:	495.62 D

From 118.00€ *

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Tefinostat

Item number: TGM-T17028-100mg

Description: Tefinostat (CHR-2845) is a potent monocyte/macrophage-targeted histone deacetylase (HDAC) inhibitor that is cleaved to the active acid CHR-2847 by intracellular esterase human carboxylesterase-1 (hCE-1). Tefinostat exhibits antitumor activity and can be used in the study of leukemia and advanced...

Keywords:	CHR-2845
CAS	914382-60-8
MW:	495.61 D

From 91.00€ *

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