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9-amino-CPT
Item number: TGM-T3S1957-100mg
Description: 9-amino-CPT (Aminocamptothecin) is an inhibitor of topoisomerase I with potent anticancer activity. Target: Topoisomerase. Smiles: CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4cccc(N)c4cc3Cn1c2=O. References: de Souza PL, et al. 9-Aminocamptothecin: a topoisomerase I inhibitor with preclinical activity in prostate...
| Keywords: | 9-amino-2(S)-camptothecin, Aminocamptothecin, 9-Aminocamptothecin |
| Application: | Topoisomerase I inhibitor |
| CAS | 91421-43-1 |
| MW: | 363.37 D |
From 37.00€
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9-amino Camptothecin
Item number: Cay17232-10
DNA topoisomerases relax supercoiled DNA during replication, transcription, recombination, repair, and chromosome condensation. The relaxation of DNA supercoiling by topoisomerase I at single-strand breaks represents a target for anticancer agents to intercalate between DNA base pairs, leading to the activation of...
| Keywords: | NSC 603071, (4S)-10-amino-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione |
| Application: | Topoisomerase I inhibitor |
| CAS | 91421-43-1 |
| MW: | 363.4 D |
From 44.00€
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