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Item number: Cay22906-10

Brexpiprazole is a serotonin (5-HT) and dopamine receptor modulator that has high affinity (Ki = 1A and 5-HT2A serotonin, dopamine D2L, and alpha1B-, and alpha2C-adrenergic receptors in CHO cell membranes expressing the human receptors. It acts as a partial agonist of 5-HT1A, D2L, and D3 receptors (EC50s = 0.49,...

Keywords:	OPC 34712, 7-[4-(4-benzo[b]thien-4-yl-1-piperazinyl)butoxy]-2(1H)-quinolinone
Application:	5-HT1A-receptor agonist
CAS	913611-97-9
MW:	433.6 D

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Brexpiprazole

Item number: TGM-T2306-100mg

Description: Brexpiprazole (OPC-34712) is a partial agonist of human 5-hydroxytryptamine (5-HT) 5-HT1A and dopamine D2 receptors. Target: Dopamine Receptor, Adrenergic Receptor, 5-HT Receptor. Smiles: C(CCCOC=1C=C2C(=CC1)C=CC(=O)N2)N3CCN(C4=C5C(SC=C5)=CC=C4)CC3. References: Ishima T, et al. Eur...

Keywords:	OPC-34712
CAS	913611-97-9
MW:	433.57 D

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