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Item number: Cay38346-10

AR-9281 is an inhibitor of soluble epoxide hydrolase (sEH, IC50 = 7 nM for the human enzyme). It reduces LPS-induced increases in plasma levels of dihydroxyeicosatrienoic acids (DiHETs), prostaglandin E2 (PGE2, Cay-14010), and PGD2 (Cay-12010) in rats when administered at a dose of 3 mg/kg. AR-9281 (1 and 3 mg/kg)...

Keywords:	APAU, UC1153, N-(1-acetyl-4-piperidinyl)-N'-tricyclo[3.3.1.13,7]dec-1-yl-urea
Application:	Soluble epoxide hydrolase (sEH) inhibitor
CAS	913548-29-5
MW:	319.4 D

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