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Item number: Cay13638-1

Almorexant is a dual antagonist of orexin 1 receptor (OX1R) and OX2R (Kis = 4.7 and 0.9 nM, respectively, in a radioligand binding assay). It decreases the latency to persistent non-rapid eye movement (NREM) sleep and increases the duration of NREM and REM sleep in male rats when administered at a dose of 100 mg/kg....

Keywords:	ACT 078573,...
Application:	HCRTR1/2 antagonist
CAS	913358-93-7
MW:	549 D

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